ea0035p634 | Female reproduction | ECE2014
van Houten E Leonie A F
, Hoek Jeffrey
, Kramer Piet
, McLuskey Anke
, Karels Bas
, Themmen Axel P N
, Visser Jenny A
Polycystic ovary syndrome (PCOS) is a disorder associated with infertility and metabolic disturbances. Ovaries of PCOS women contain an increased number of growing follicles. Such an ovarian phenotype is also observed in mice lacking the ovary-specific growth factor anti-Müllerian hormone (AMH). To determine the interaction between ovarian and metabolic function, we studied the metabolic phenotype of mice lacking AMH signaling as a model for an altered profile in ovarian ...